国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (4): 364-368.doi: 10.3760/ cma.j.issn.1673-5803.2021.04.018

• 综述 • 上一篇    

IgG4相关性眼病与眼附属器淋巴瘤的关系及鉴别

柳睿 马建民   

  1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 眼科学与视觉科学北京市重点实验室 100730
  • 收稿日期:2020-08-02 出版日期:2021-08-22 发布日期:2021-08-30
  • 通讯作者: 马建民,Email:jmma@sina.com E-mail:jmma@sina.com
  • 基金资助:
    北京市自然科学基金(7182038);北京市医院管理中心“登峰”计划专项基金(DFL20190201)

Relationship and differential diagnosis between IgG4-related ocular diseases and ocular adnexal lymphoma

Liu Rui, Ma Jianmin   

  1. Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2020-08-02 Online:2021-08-22 Published:2021-08-30
  • Contact: Ma Jianmin, Email: jmma@sina.com E-mail:jmma@sina.com
  • Supported by:
    Beijing Natural Science Foundation (7182038); Beijing Hospitals Authority Ascent Plan (DFL20190201)

摘要: IgG4相关性眼病(immunoglobulinG4-related ophthalmic disease,IgG4-ROD)是一种较为常见的眼部疾病,可以发展为淋巴瘤,但发生机制未明。眼附属器淋巴瘤是成年人最常见的发生于眼部的恶性肿瘤。IgG4-ROD和眼附属器淋巴瘤的临床表现和影像学特征具有相似性,故仅凭临床表现和影像学改变来鉴别两者具有困难;病理组织学检查和基因检测结果目前仍然是鉴定两者的金标准。(国际眼科纵览,2021, 45: 364-368)

关键词: IgG4相关性眼病, 眼附属器淋巴瘤, 鉴别诊断

Abstract: Immunoglobuling4-related ophthalmic disease (IgG4-ROD) is a common ocular disease that can develop into lymphoma, but the mechanism of its occurrence is unknown. Ocular adnexal lymphoma is the most common ocular malignancy in adults. The clinical manifestations and imaging features of IgG4-ROD and ocular adnexal lymphoma are similar, so it is difficult to distinguish them based on clinical manifestations and imaging changes alone. The results of histopathological examination and genetic test are still the gold standard for the identification of them.(Int Rev Ophthalmol, 2021, 45: 364-368)

Key words: immunoglobulin 4-related ophthalmic disease, ocular adnexal lymphoma, differential diagnosis